AH
PBM Research974 studies

Photobiomodulation for Oral

974 peer-reviewed studies on light therapy for oral, spanning 1988 to 2020. Filtered from the full PBM database of 4,914 studies.

974

Total Studies

556

Human Studies

816

Positive Results

6

Wavelength Bands

Study Types

Human
556 (57%)
Rat
125 (13%)
Review
122 (13%)
In vitro
78 (8%)
Animal
64 (7%)
Rabbit
23 (2%)

Outcomes

positive
816 (84%)
unclear
149 (15%)
negative
9 (1%)

Wavelength Distribution

Not specified

348 studies

Near-IR (700-900nm)

286 studies

Red (600-700nm)

210 studies

IR (900nm+)

124 studies

Blue (<500nm)

3 studies

Green (500-600nm)

3 studies

All Studies (974)

Photobiomodulation therapy for the management of recurrent aphthous stomatitis in children: clinical effectiveness and parental satisfaction.

BardelliniMed Oral Patol Oral Cir Bucal2020
positiveHuman

Influence of low-level laser therapy on inflammation, collagen fiber maturation, and tertiary dentin deposition in the pulp of bleached teeth.

TerayamaClin Oral Investig2020
positiveRat

Efficacy of low-level laser therapy as an adjunct to non-surgical mechanical debridement in the treatment of peri-implantitis.

AlgahtaniJ Oral Implantol2020
positiveHuman

Can Low-Level Laser and Light-Emitting Diode Enhance the Stability of Dental Implants?

MohajeraniJ Maxillofac Oral Surg2020
positiveHuman

Influence of low-level laser therapy on implant stability in implants placed in fresh extraction sockets: A randomized clinical trial.

LobatoClin Implant Dent Relat Res2020
positiveHuman

Evaluation of effectiveness of photobiostimulation in alleviating side effects after dental implant surgery. A randomized clinical trial.

CaccianigaMed Oral Patol Oral Cir Bucal2020
positiveHuman

Evaluation of photobiomodulation in salivary production of patients with xerostomy induced by anti-hypertensive drugs: Study protocol clinical trial (SPIRIT compliant).

VarellisMedicine (Baltimore)2020
unclearAnimal

Photobiomodulation Therapy for Cancer Treatment-Related Salivary Gland Dysfunction: A Systematic Review.

HeiskanenPhotobiomodul Photomed Laser Surg2020
unclearReview

Combined effects of calcium hydroxide and photobiomodulation therapy on apexogenesis of immature permanent teeth in dogs.

BahmanJ Photochem Photobiol B2020810nm
positiveAnimal

Photobiomodulation effect on angiogenic proteins produced and released by dental pulp cells.

VitorClin Oral Investig2020660nm
positiveIn vitro

Dopaminergic induction of human dental pulp stem cells by photobiomodulation: comparison of 660nm laser light and polychromatic light in the nir.

YurtseverJ Photochem Photobiol B2020
positiveIn vitro

Angiogenic protein synthesis after photobiomodulation therapy on SHED: a preliminary study.

Oliveira Prado BergamoLasers Med Sci2020660nm
positiveIn vitro

Photobiomodulation therapy improves human dental pulp stem cell viability and migration in vitro associated to upregulation of histone acetylation.

ZaccaraLasers Med Sci2020660nm
positiveIn vitro

The photobiomodulation therapy together with the use of cord blood platelet gel could be safely suggested as primary treatment for oral lesions in patients with inherited epidermolysis bullosa.

SindiciPhotodermatol Photoimmunol Photomed2020645nm
positiveHuman

Photobiomodulation and photodynamic therapy for the management of oral graft-versus-host disease: a case report.

CamposPhotodiagnosis Photodyn Ther2020660nm
unclearHuman

Low-level laser therapy for neurosensory recovery after sagittal ramus osteotomy

Pinto FariaMinerva Stomatol2020808nm
positiveHuman

Effect of photobiomodulation on recovery from neurosensory disturbances after sagittal split ramus osteotomy: a triple-blind randomised controlled trial.

SharifiBr J Oral Maxillofac Surg2020980nm
positiveHuman

Recovery of inferior alveolar nerve by photobiomodulation therapy using two laser wavelengths: A behavioral and immunological study in rat.

HakimihaJ Photochem Photobiol B2020
positiveRat

Effectiveness of low-level laser therapy for oral mucositis prevention in patients undergoing chemoradiotherapy for the treatment of head and neck cancer: A systematic review and meta-analysis.

de LimaOral Oncol2020
unclearReview

Photobiomodulation and B vitamins administration produces antinociception in an orofacial pain model through the modulation of glial cells and cytokines expression

MatrtinsBrain Behav Immun2020904nm
positiveRat

Effects of photobiomodulation at different wavelengths on orthodontically induced root resorption in orthodontic retention period: a micro-CT and RT-PCR study.

Ozturk & Gul AmukLasers Med Sci2020
negativeRat

Effectiveness of low-level laser therapy in accelerating the orthodontic tooth movement: A systematic review and meta-analysis.

Bakdach & HadadDent Med Probl2020
unclearReview

Assessment of a single versus double application of low-level laser therapy in pain reduction following orthodontic elastomeric separation: A randomized controlled trial.

AlmallahDent Med Probl2020830nm
positiveHuman

The Effect of Low-Level Laser Therapy on the Acceleration of Orthodontic Tooth Movement.

Baghizadeh FiniJ Lasers Med Sci2020
unclearReview

The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blind, split-mouth, randomized controlled trial.

MistryAm J Orthod Dentofacial Orthop2020
positiveHuman

Evaluation of the effects of photobiomodulation on orthodontic movement of molar verticalization with mini-implant: A randomized double-blind protocol study.

Murakami-Malaquias-SilvaMedicine (Baltimore)2020
positiveAnimal

A Comparative Assessment of Pain Caused by the Placement of Banded Orthodontic Appliances with and without Low-Level Laser Therapy: A Randomized Controlled Prospective Study.

NicotraDent J (Basel)2020980nm
positiveHuman

The effect of low-level light therapy on orthodontic tooth movement rate, heat shock protein 70, and matrix metallopreteinase 8 expression: Animal study.

NarmadaDent Res J (Isfahan)2020810nm
positiveAnimal

A Comparative Assessment of the Efficiency of Orthodontic Treatment With and Without Photobiomodulation During Mandibular Decrowding in Young Subjects: A Single-Center, Single-Blind Randomized Controlled Trial.

Lo GiudicePhotobiomodul Photomed Laser Surg2020
positiveHuman

Effect of Low Intensity Laser Therapy (LILT) on MMP-9 expression in gingival crevicular fluid and rate of orthodontic tooth movement in patients undergoing canine retraction: A randomized controlled trial.

JivrajaniInt Orthod2020
positiveHuman

The Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Report.

Del Pilar Rodríguez-SánchezJ Lasers Med Sci2020808nm
positiveHuman

Effectiveness of laser-assisted treatments for medication-related osteonecrosis of the jaw: a systematic review.

LiBr J Oral Maxillofac Surg2020
unclearHuman

Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws: case series and long-term follow-up.

TartarotiPhotodiagnosis Photodyn Ther2020
positiveHuman

The Combination of Antimicrobial Photodynamic Therapy and Photobiomodulation Therapy for the Treatment of Palatal Ulcers: A Case Report.

MayaJ Lasers Med Sci2020660nm
positiveHuman

Efficacy of antimicrobial photodynamic and photobiomodulation therapy against Treponema denticola, fusobacterium nucleatum and human beta defensin-2 levels in patients with gingivitis undergoing fixed orthodontic treatment: A clinic-laboratory study.

Algerban APhotodiagnosis Photodyn Ther2020810nm
positiveHuman

Effect of diode laser application as an adjunct to nonsurgical periodontal therapy on the reduction of red complex microorganisms in type 2 diabetics with chronic periodontitis.

KocakLasers Med Sci2020940nm
positiveHuman

Adjunctive effects of laser therapy on somatosensory function and vasomotor regulation of periodontal tissues in patients with periodontitis- A randomized controlled clinical trial.

GouJ Periodontol2020
positiveHuman

Effect of photobiomodulation therapy as an adjunct to scaling and root planing in a rat model of ligature-induced periodontitis: a histological and radiographic study.

PereiraLasers Med Sci2020
positiveRat

Is low level laser therapy or ozone therapy more effective for bone healing? Understanding the mechanisms of HIF-1α, RANKL and OPG.

Bayer AlincaBiotech Histochem2020810nm
positiveRat

Photobiomodulation (450 nm) alters the infection of periodontitis bacteria via the ROS/MAPK/mTOR signaling pathway.

LiFree Radic Biol Med2020450nm
positiveRat

Photobiomodulation of inflammatory-cytokine-related effects in a 3-D culture model with gingival fibroblasts.

CardosoLasers Med Sci2020780nm
positiveIn vitro

Photobiomodulation therapy inhibits oral submucous fibrosis in mice.

ChiangOral Dis2020660nm
positiveMouse

Comparative efficacy of low-Level laser and TENS in the symptomatic relief of temporomandibular joint disorders: A randomized clinical trial.

Chellappa & ThirupathyIndian J Dent Res2020
positiveHuman

Efficacy of Low-Level Laser, Hard Occlusal Appliance and Conventional Pharmacotherapy in the Management of Myofascial Pain Dysfunction Syndrome; A Preliminary Study.

Azangoo KhiaviJ Lasers Med Sci2020940nm
positiveHuman

The influence of educational measures and low-level laser phototherapy on temporomandibular disorders: Study protocol clinical trial (SPIRIT Compliant).

DantasMedicine (Baltimore)2020808nm
unclearAnimal

Photobiomodulation Therapy for Myofascial Pain in Temporomandibular Joint Dysfunction: A Double-Blinded Randomized Clinical Trial.

NadershahJ Maxillofac Oral Surg2020940nm
positiveHuman

Consequences of 660 nm Diode Laser Following Postsurgical Exodontia in Patients under Contraceptive Pills: A Randomized Double-blinded Clinical Trial.

Salem SJ Contemp Dent Pract2020660nm
positiveHuman

The Effect of Cigarette Smoking And Low-Level Laser Irradiation in RANK/RANKL/OPG Expression.

RibeiroBraz Dent J2020830nm
negativeRat

Comparative evaluation of Low Level Laser Therapy and cryotherapy in pain control and wound healing following orthodontic tooth extraction: A double blind study.

JohnJ Craniomaxillofac Surg2020
positiveHuman

Photobiomodulation as an adjunctive therapy for alveolar socket preservation: a preliminary study in humans.

RoseroLasers Med Sci2020808nm
positiveHuman
Back to Full PBM Database

Related Products

Light Therapy Devices

FDA-cleared PBM devices, clinically reviewed

Continue Exploring

Sauna & Heat Therapy

1,945 studies

Cold Exposure

2,784 studies

Join the Discussion

Connect with others researching photobiomodulation. Share protocols, results, and questions.

How to Use This Site

Learn how products, research, protocols, and community connect across the platform.