PBM Research104 studies
Photobiomodulation for Eyes
104 peer-reviewed studies on light therapy for eyes, spanning 1987 to 2020. Filtered from the full PBM database of 4,914 studies.
104
Total Studies
25
Human Studies
84
Positive Results
3
Wavelength Bands
Study Types
Rat
30 (29%)
Human
25 (24%)
Mouse
14 (13%)
Review
13 (13%)
Animal
9 (9%)
Rabbit
7 (7%)
Outcomes
positive
84 (81%)
unclear
16 (15%)
negative
4 (4%)
Wavelength Distribution
Red (600-700nm)
56 studies
Not specified
39 studies
Near-IR (700-900nm)
9 studies
All Studies (104)
Photobiomodulation Mediates Neuroprotection against Blue Light Induced Retinal Photoreceptor Degeneration
HeinigInt J Mol Sci2020
positiveMouse
Safety Profile of Slit-Lamp-Delivered Retinal Laser Photobiomodulation
AoTransl Vis Sci Technol2020670nm
positiveRat
A double-masked, randomized, sham-controlled, single-center study with photobiomodulation for the treatment of dry age-related macular degeneration.
MarkowitzRetina2019
positiveHuman
Improving mitochondrial function significantly reduces the rate of age related photoreceptor loss.
SivapathasuntharamExp Eye Res2019670nm
positiveMouse
Low-power lasers on amblyopia
Paiva & FonsecaLaser Phys Lett2019
unclearReview
Low level light therapy for the treatment of recalcitrant chalazia: a sample case summary.
Stonecipher & PotvinClin Ophthalmol2019
positiveHuman
Enhancement of corneal epithelium cell survival, proliferation and migration by red light: Relevance to corneal wound healing.
Núñez-Álvarez & OsborneExp Eye Res2019
negativeIn vitro
The combined effect of photobiomodulation therapy and chia seeds supplementation for the treatment of diabetic retinopathy in experimental rats
AbdelkawiJ Arab Soc Med Res2019670nm
positiveRat
Effects of Low-level Light Therapy at 740 nm on Dry Eye Disease In Vivo
GooMedical Lasers; Engineering, Basic Research, and Clinical Application2019740nm
positiveMouse
Combined low level light therapy and intense pulsed light therapy for the treatment of meibomian gland dysfunction.
StonecipherClin Ophthalmol2019
positiveHuman
Blue light exacerbates and red light counteracts negative insults to retinal ganglion cells in situ and R28 cells in vitro.
Núñez‐ÁlvarezNeurochem Int2019
negativeIn vitro
Blue light negatively affects the survival of ARPE19 cells through an action on their mitochondria and blunted by red light.
Núñez-ÁlvarezActa Ophthalmol2019
positiveIn vitro
Effects of the long wavelength-filtered continuous spectrum on natural refractive development in juvenile guinea pigs.
LiInt J Ophthalmol2019
positiveAnimal
The effect of infra-red light on intraocular pressure.
DimitrovaArq Bras Oftalmol2019
positiveHuman
A pilot randomised clinical trial of 670 nm red light for reducing retinopathy of prematurity.
KentPediatr Res2019670nm
positiveHuman
Five-year follow-up of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD)
KoevCONFERENCE PAPER: Journal of Physics2018633nm
positiveHuman
Photobiomodulation Inhibits Long-term Structural and Functional Lesions of Diabetic Retinopathy.
ChengDiabetes2018670nm
positiveMouse
Bioptron light therapy to dry eye caused by long-term topically applied antiglaucoma drug with benzalkonium-chloride
BrankovicActa Medica Medianae2018
positiveHuman
Blue light negatively affects the survival of ARPE19 cells through an action on their mitochondria and blunted by red light.
Núñez‐ÁlvarezActa Ophthalmol2018630nm
negativeIn vitro
Make lighting healthier.
Zielinska-Dabkowska KMNature2018
unclearAnimal
670nm light treatment following retinal injury modulates Müller cell gliosis: Evidence from in vivo and in vitro stress models
LuExp Eye Res2018670nm
positiveRat
Effects of Light of Different Spectral Composition on Refractive Development and Retinal Dopamine in Chicks.
WangInvest Ophthalmol Vis Sci2018
positiveAnimal
Narrow-band, long-wavelength lighting promotes hyperopia and retards vision-induced myopia in infant rhesus monkeys.
HungExp Eye Res2018630nm
positiveAnimal
Physical treatments for age-related macular degeneration
WaughBOOK: Treatments for dry age-related macular degeneration and Stargardt disease: a systematic review2018
unclearReview
Aging retinal function is improved by near infrared light (670 nm) that is associated with corrected mitochondrial decline.
SivapathasuntharamNeurobiol Aging2017670nm
positiveMouse
Near infra-red light attenuates corneal endothelial cell dysfunction in situ and in vitro.
Núñez-ÁlvarezExp Eye Res2017
negativeRat
Photobiomodulation with 670 nm light ameliorates Müller cell-mediated activation of microglia and macrophages in retinal degeneration.
LuExp Eye Res2017670nm
positiveRat
The wavelength composition and temporal modulation of ambient lighting strongly affect refractive development in young tree shrews.
GawneExp Eye Res2017
positiveAnimal
Long-wavelength (red) light produces hyperopia in juvenile and adolescent tree shrews.
GawneVision Res2017
positiveAnimal
Light-Emitting Diode (LED) therapy improves occipital cortex damage by decreasing apoptosis and increasing BDNF-expressing cells in methanol-induced toxicity in rats.
GhanbariBiomed Pharmacother2017670nm
positiveRat
Retinal pigment epithelium in the pathogenesis of age-related macular degeneration and photobiomodulation as a potential therapy?
AoClin Exp Ophthalmol2017
unclearReview
Protective treatments and their target retinal ganglion cells in diabetic retinopathy.
ZhangBrain Res Bull2017
unclearReview
Photostimulation of mitochondria as a treatment for retinal neurodegeneration.
BeirneMitochondrion2017
unclearReview
Photobiomodulation reduces drusen volume and improves visual acuity and contrast sensitivity in dry age-related macular degeneration.
MerryActa Ophthalmol2016
positiveHuman
Short-term effects of extremely low-frequency pulsed electromagnetic field and pulsed low-level laser therapy on rabbit model of corneal alkali burn.
Rezaei KanaviExp Eye Res2016810nm
positiveRabbit
Efficacy of 670 nm Light Therapy to Protect against Photoreceptor Cell Death Is Dependent on the Severity of Damage
Chu-TanInt J Photoenergy2016670nm
positiveRat
Optical monitoring of retinal respiration in real time: 670 nm light increases the redox state of mitochondria.
KaynezhadExp Eye Res2016670nm
positiveRat
Red Light Treatment in an Axotomy Model of Neurodegeneration.
BeirnePhotochem Photobiol2016670nm
positiveMouse
Red light of the visual spectrum attenuates cell death in culture and retinal ganglion cell death in situ.
Del Olmo-AguadoActa Ophthalmol2016630nm
positiveRat
Targeting mitochondrial function to treat optic neuropathy.
GuevenMitochondrion2016
unclearReview
Mechanistic Insights into Pathological Changes in the Diabetic Retina: Implications for Targeting Diabetic Retinopathy
RoyAm J Pathol2016
unclearReview
Photobiomodulation for the treatment of retinal diseases: a review.
Geneva (Ivayla)Int J Ophthalmol2016
unclearReview
Near-Infrared Photobiomodulation in Retinal Injury and Disease.
EellsAdv Exp Med Biol2016
unclearReview
Glaucoma: Focus on mitochondria in relation to pathogenesis and neuroprotection.
OsborneEur J Pharmacol2016
unclearReview
Visual light effects on mitochondria: The potential implications in relation to glaucoma.
OsborneMitochondrion2016
unclearReview
Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light.
CalazaNeurobiol Aging2015670nm
positiveMouse
Photobiomodulation Mitigates Diabetes-Induced Retinopathy by Direct and Indirect Mechanisms: Evidence from Intervention Studies in Pigmented Mice.
SalibaPLoS One2015670nm
positiveMouse
Effects of Photobiomodulation Therapy on Patients with Primary Open Angle Glaucoma: A Pilot Study. [RETRACTED ARTICLE]
Ivandic & IvandicPhotomed Laser Surg2015780nm
positiveHuman
Photobiomodulation with 670 nm light increased phagocytosis in human retinal pigment epithelial cells.
FumaMol Vis2015
positiveHuman
The myopia boom.
Dolgin ENature2015
unclearAnimal