PBM Research167 studies
Photobiomodulation for Cells
167 peer-reviewed studies on light therapy for cells, spanning 1984 to 2020. Filtered from the full PBM database of 4,914 studies.
167
Total Studies
2
Human Studies
154
Positive Results
4
Wavelength Bands
Study Types
In vitro
154 (92%)
Review
8 (5%)
Mouse
2 (1%)
Human
2 (1%)
Rat
1 (1%)
Outcomes
positive
154 (92%)
unclear
10 (6%)
negative
3 (2%)
Wavelength Distribution
Red (600-700nm)
71 studies
Not specified
60 studies
Near-IR (700-900nm)
21 studies
IR (900nm+)
15 studies
All Studies (167)
Biphasic Dose/Response of Photobiomodulation Therapy on Culture of Human Fibroblasts.
Flores LunaPhotobiomodul Photomed Laser Surg2020660nm
positiveIn vitro
RNA-Seq analysis revealed the molecular mechanisms of photobiomodulation effect on human fibroblasts.
LiPhotodermatol Photoimmunol Photomed2020
positiveIn vitro
Photobiomodulation with 630-nm LED radiation inhibits the proliferation of human synoviocyte MH7A cells possibly via TRPV4/PI3K/AKT/mTOR signaling pathway.
MengLasers Med Sci2020630nm
positiveIn vitro
A Comprehensive Analysis of Near‐Contact Photobiomodulation Therapy in the Host–Bacteria Interaction Model Using 3D‐Printed Modular LED Platform
KimAdv Biosyst2020
positiveIn vitro
Beyond 2D: effects of photobiomodulation in 3D tissue-like systems.
BikmulinaJ Biomed Opt2020
positiveIn vitro
Photobiomodulation alters the viability of HUVECs cells.
TerenaLasers Med Sci2020
positiveIn vitro
Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing.
FerroniJ Clin Med2020
positiveIn vitro
Photobiomodulation and the expression of genes related to the JAK/STAT signalling pathway in wounded and diabetic wounded cells.
JereJ Photochem Photobiol B2020660nm
positiveIn vitro
Activation of the extracellular signal-regulated kinase signal pathway by light emitting diode irradiation.
KomineLasers Med Sci2020627nm
positiveIn vitro
Photobiomodulation can alter mRNA levels cell death-related.
da SilvaLasers Med Sci2019830nm
positiveMouse
Effects of photobiomodulation on mitochondria of brain, muscle, and C6 astroglioma cells.
SilveiraMed Eng Phys2019660nm
positiveIn vitro
Photobiomodulation at 660 nm Stimulates Fibroblast Differentiation.
MokoenaLasers Med Sci2019660nm
positiveIn vitro
Human Fibroblast Gene Expression Modulation Using 940 NM Diode Laser.
Illescas-MontesSci Rep2019940nm
positiveIn vitro
Photobiomodulation therapy can change actin filaments of 3T3 mouse fibroblast.
de MagalhãesLasers Med Sci2019
positiveIn vitro
Effect of Photobiomodulation on Secretion of IL-6 and IL-8 by Human Gingival Fibroblasts In Vitro.
HarorliPhotobiomodul Photomed Laser Surg2019940nm
positiveIn vitro
Interaction between low-level laser therapy and Guarana (Paullinia cupana) extract induces antioxidant, anti-inflammatory, and anti-apoptotic effects and promotes proliferation in dermal fibroblasts.
MaldanerJ Cosmet Dermatol2019660nm
positiveIn vitro
In vitro effect of low-level laser therapy on the proliferative, apoptosis modulation, and oxi-inflammatory markers of premature-senescent hydrogen peroxide-induced dermal fibroblasts.
MaldanerLasers Med Sci2019660nm
negativeIn vitro
Light-emitting diode irradiation using 660 nm promotes human fibroblast HSP90 expression and changes cellular activity and morphology.
ChoiJ Biophotonics2019660nm
positiveIn vitro
Combined treatment of low-level laser therapy and phloroglucinol for inhibition of fibrosis.
LeeLasers Surg Med2019635nm
positiveIn vitro
Photobiomodulation effects on keratinocytes cultured in vitro: a critical review
de AbreuLasers Med Sci2019
unclearReview
Protective effect of Photobiomodulation Therapy and Bone Marrow Stromal Stem Cells Conditioned Media on Pheochromocytoma Cell Line 12 Against Oxidative Stress Induced by Hydrogen Peroxide.
KhoshsiratJ Lasers Med Sci2019633nm
positiveIn vitro
Photobiomodulation (660 nm) therapy reduces oxidative stress and induces BDNF expression in the hippocampus.
HeoSci Rep2019660nm
positiveIn vitro
Photobiomodulation increases cell viability via AKT activation in an in vitro model of diabetes induced by glucose neurotoxicity.
da Silva OliveiraLasers Med Sci2019660nm
positiveIn vitro
Low-level laser therapy alleviates the deleterious effect of doxorubicin on rat adipose tissue-derived mesenchymal stem cells.
de LimaJ Photochem Photobiol B2019660nm
positiveIn vitro
Effect of photobiomodulation therapy on neuronal injuries by ouabain: the regulation of Na, K-ATPase; Src; and mitogen-activated protein kinase signaling pathway.
RheeBMC Neurosci2019660nm
positiveIn vitro
Cell Adhesion Molecules are Mediated by Photobiomodulation at 660 nm in Diabetic Wounded Fibroblast Cells.
HoureldCells2018660nm
positiveIn vitro
Low power lasers on genomic stability
da Silva Neto Trajano (??)J Photochem Photobiol B2018
unclearReview
Photobiomodulation with 808-nm diode laser light promotes wound healing of human endothelial cells through increased reactive oxygen species production stimulating mitochondrial oxidative phosphorylation.
AmaroliLasers Med Sci2018808nm
positiveIn vitro
Differential response of human dermal fibroblast subpopulations to visible and near-infrared light: Potential of photobiomodulation for addressing cutaneous conditions.
MignonLasers Surg Med2018
positiveIn vitro
The effect of polarized light on the organization of collagen secreted by fibroblasts.
AkilbekovaLasers Med Sci2018800nm
positiveIn vitro
Effect of 660 nm visible red light on cell proliferation and viability in diabetic models in vitro under stressed conditions.
AyukLasers Med Sci2018660nm
positiveIn vitro
Erythrocytic bioactivation of nitrite and its potentiation by far-red light.
WajihRedox Biol2018660nm
positiveRat
Ascorbate attenuates red light mediated vasodilation: Potential role of S-nitrosothiols.
KeszlerRedox Biol2018670nm
positiveIn vitro
Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide.
OsipovFront Med (Lausanne)2018
unclearReview
Photobiomodulation induces in vitro re-epithelialization via nitric oxide production.
RizziLasers Med Sci2018980nm
positiveIn vitro
Effect of Laser Irradiation on Cell Cycle and Mitosis.
GanjaliJ Lasers Med Sci2018633nm
positiveIn vitro
LED enhances anti-inflammatory effect of luteolin (3',4',5,7-tetrahydroxyflavone) in vitro.
FanAm J Transl Res2018
positiveIn vitro
Effect of red light and near infrared laser on the generation of reactive oxygen species in primary dermal fibroblasts
GeorgeJ Photochem Photobiol B2018
positiveIn vitro
Wound-healing effects of 635-nm low-level laser therapy on primary human vocal fold epithelial cells: an in vitro study.
LouLasers Med Sci2018635nm
positiveIn vitro
Effect of NIR photobiomodulation therapy in a cellular wound healing model.
KönigPhotodermatol Photoimmunol Photomed2018
positiveIn vitro
Photobiomodulation therapy promotes in vitro wound healing in nicastrin KO HaCaT cells.
TricaricoJ Biophotonics2018970nm
positiveIn vitro
Photobiomodulation at 660nm stimulates proliferation and migration of diabetic wounded cells via the expression of epidermal growth factor and the JAK/STAT pathway.
JereJ Photochem Photobiol B2018660nm
positiveIn vitro
Red (660 nm) or near-infrared (810 nm) photobiomodulation stimulates, while blue (415 nm), green (540 nm) light inhibits proliferation in human adipose-derived stem cells.
WangSci Rep2017
positiveIn vitro
Photobiomodulation alters matrix protein activity in stressed fibroblast cells in vitro.
AyukJ Biophotonics2017
positiveIn vitro
The effects of low level laser irradiation on proliferation of human dental pulp: a narrative review.
StaffoliClin Ter2017
unclearReview
The impact of wavelengths of LED light-therapy on endothelial cells.
RohringerSci Rep2017
positiveIn vitro
A Comparative Study of 660 nm Low-Level Laser and Light Emitted Diode in Proliferative Effects of Fibroblast Cells.
NaderiJ Lasers Med Sci2017660nm
positiveIn vitro
Low-level laser irradiation induces in vitro proliferation of stem cells from human exfoliated deciduous teeth.
GinaniLasers Med Sci2017660nm
positiveIn vitro
The Effects of Photobiomodulation Delivered by Light-Emitting Diode on Stem Cells from Human Exfoliated Deciduous Teeth: A Study on the Relevance to Pluripotent Stem Cell Viability and Proliferation.
ValePhotomed Laser Surg2017630nm
positiveIn vitro
LLLT Effects on Oral Keratinocytes in an Organotypic 3D Model.
BassoPhotochem Photobiol2017780nm
positiveIn vitro