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PBM Research243 studies

Photobiomodulation for Brain

243 peer-reviewed studies on light therapy for brain, spanning 1990 to 2020. Filtered from the full PBM database of 4,914 studies.

243

Total Studies

61

Human Studies

181

Positive Results

4

Wavelength Bands

Study Types

Mouse
63 (26%)
Human
61 (25%)
Rat
42 (17%)
Review
40 (16%)
Animal
18 (7%)
In vitro
13 (5%)

Outcomes

positive
181 (74%)
unclear
57 (23%)
negative
5 (2%)

Wavelength Distribution

Not specified

114 studies

Near-IR (700-900nm)

58 studies

Red (600-700nm)

54 studies

IR (900nm+)

17 studies

All Studies (243)

Photobiomodulation for Alzheimer's Disease: Translating Basic Research to Clinical Application.

EnenglJ Alzheimers Dis2020
unclearReview

Nutritional Ketosis and photobiomodulation remediate mitochondria warding off Alzheimer's disease in a diabetic, ApoE4+ patient with mild cognitive impairment: A case report.

HornerPhotodiagnosis Photodyn Ther2020810nm
positiveHuman

Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression.

KerppersLasers Med Sci2020945nm
positiveHuman

Transcranial photobiomodulation attenuates pentylenetetrazole-induced status epilepticus in peripubertal rats.

TsaiJ Biophotonics2020808nm
positiveRat

Photostimulation of cerebral and peripheral lymphatic functions

Semyachkina‐GlushkovskayaTranslational Biophotonics20201268nm
positiveMouse

Transcranial Photobiomodulation (tPBM) With 1,064-nm Laser to Improve Cerebral Metabolism of the Human Brain In Vivo.

PruittLasers Surg Med20201064nm
positiveHuman

Effects of photobiomodulation on interleukin-10 and nitrites in individuals with relapsing-remitting multiple sclerosis - Randomized clinical trial.

SilvaPLoS One2020808nm
negativeHuman

Photobiomodulation for Parkinson's Disease in Animal Models: A Systematic Review.

Salehpour & HamblinBiomolecules2020
unclearReview

Mitochondrial Dysfunction and Parkinson's Disease-Near-Infrared Photobiomodulation as a Potential Therapeutic Strategy.

FooFront Aging Neurosci2020
unclearReview

Photobiomodulation enhances mitochondrial respiration in an in vitro rotenone model of Parkinson’s disease

BikmulinaOpt Eng2020
positiveIn vitro

Light Modulation of Brain and Development of Relevant Equipment.

LiJ Alzheimers Dis2020
unclearReview

New strategies for ischemic stroke: internal photobiomodulation therapy.

Iglesias-Rey & CastilloNeural Regen Res2020
unclearAnimal

Treatment of Neurodegeneration: Integrating Photobiomodulation and Neurofeedback in Alzheimer's Dementia and Parkinson's: A Review.

Berman & NicholsPhotobiomodul Photomed Laser Surg2019
positiveHuman

New insight into Alzheimer's disease: Light reverses Aβ-obstructed interstitial fluid flow and ameliorates memory decline in APP/PS1 mice.

YueAlzheimers Dement (N Y)2019
positiveMouse

Activation of PKA/SIRT1 signaling pathway by photobiomodulation therapy reduces Aβ levels in Alzheimer's disease models.

ZhangAging Cell2019633nm
positiveMouse

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer’s disease

ZinchenkoBiomed Opt Express20191267nm
positiveMouse

Photobiomodulation for Alzheimer’s Disease: Has the Light Dawned?

Hamblin MRPhotonics2019
unclearReview

Rapid Reversal of Cognitive Decline, Olfactory Dysfunction, and Quality of Life Using Multi-Modality Photobiomodulation Therapy: Case Report.

SalehpourPhotobiomodul Photomed Laser Surg2019
positiveHuman

Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial.

Chao LLPhotobiomodul Photomed Laser Surg2019810nm
positiveHuman

Transcranial Photobiomodulation with Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study.

MaielloPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman

Intracerebral Transcatheter Laser Photobiomodulation Therapy in the Treatment of Binswanger's Disease and Vascular Parkinsonism: Research and Clinical Experience.

Maksimovich IVPhotobiomodul Photomed Laser Surg2019633nm
positiveHuman

Transcranial Photobiomodulation to Augment Lithium in Bipolar-I Disorder.

MannuPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman

Photobiomodulation Therapy for Repeated Closed Head Injury in Rats.

YangJ Biophotonics2019808nm
positiveRat

Transcranial Photobiomodulation Therapy in the Cognitive Rehabilitation of Patients with Cranioencephalic Trauma.

CarneiroPhotobiomodul Photomed Laser Surg2019630nm
positiveHuman

Photobiomodulation preconditioning prevents cognitive impairment in a neonatal rat model of hypoxia-ischemia.

YangJ Biophotonics2019808nm
positiveRat

Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System

LeeTrans Electr Electron Mater2019810nm
positiveMouse

Brain Photobiomodulation-Preliminary Results from Regional Cerebral Oximetry and Thermal Imaging.

Litscher GMedicines (Basel)2019810nm
positiveHuman

Can Mild Cognitive Impairment Be Stabilized By Showering Brain Mitochondria With Laser Photons?

de la TorreNeuropharmacology2019
unclearReview

Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis.

SalehpourPhotobiomodul Photomed Laser Surg2019
unclearReview

Cognitive Enhancement by Transcranial Photobiomodulation Is Associated With Cerebrovascular Oxygenation of the Prefrontal Cortex.

HolmesFront Neurosci20191064nm
positiveHuman

Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives

Askalsky & IosifescuNeuropsychiatr Dis Treat2019
unclearReview

Near-infrared photobiomodulation combined with coenzyme Q10 for depression in a mouse model of restraint stress: reduction in oxidative stress, neuroinflammation, and apoptosis.

SalehpourBrain Res Bull2019810nm
positiveMouse

Transcranial photobiomodulation prevents anxiety and depression via changing serotonin and nitric oxide levels in brain of depression model mice: A study of three different doses of 810 nm laser.

EshaghiLasers Surg Med2019810nm
positiveMouse

Transcranial Photobiomodulation for Down Syndrome.

MannuPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman

Brain Photobiomodulation: A New Strategy to Enhance Cognitive Function?

Gaggioli ACyberpsychol Behav Soc Netw2019
unclearAnimal

Transcranial photobiomodulation with 1064-nm laser modulates brain electroencephalogram rhythms.

WangNeurophotonics2019
positiveHuman

Transcranial near-infrared photobiomodulation could modulate brain electrophysiological features and attentional performance in healthy young adults.

JahanLasers Med Sci2019850nm
positiveHuman

Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study.

ZomorrodiSci Rep2019810nm
positiveHuman

Transcranial near-infrared stimulation may increase cortical excitability recorded in humans.

SongBrain Res Bull2019820nm
positiveHuman

Exploring the Effects of Near Infrared Light on Resting and Evoked Brain Activity in Humans Using Magnetic Resonance Imaging.

El KhouryNeuroscience2019810nm
positiveHuman

Short-term Effects of Transcranial Near-Infrared Photobiomodulation on Motor Performance in Healthy Human Subjects: An Experimental SingleBlind Randomized Clinical Trial.

FekriJ Lasers Med Sci2019808nm
positiveHuman

"Buckets": Early Observations on the Use of Red and Infrared Light Helmets in Parkinson's Disease Patients.

HamiltonPhotobiomodul Photomed Laser Surg2019
positiveHuman

Photobiomodulation Mitigates Cerebrovascular Leakage Induced by the Parkinsonian Neurotoxin MPTP.

San MiguelBiomolecules2019670nm
positiveMouse

Effect of Photobiomodulation in Rescuing Lipopolysaccharide-Induced Dopaminergic Cell Loss in the Male Sprague-Dawley Rat.

O'Brien & AustinBiomolecules2019
positiveRat

Parkinson's Disease and Light: The Bright and the Dark Sides.

MaggioBrain Res Bull2019
unclearReview

Photobiomodulation in Parkinson's disease: A randomized controlled trial

SantosBrain Stimul2019670nm
positiveHuman

Pre-conditioning with remote photobiomodulation modulates the brain transcriptome and protects against MPTP insult in mice.

GaneshanNeuroscience2019670nm
positiveMouse

Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review.

SalehpourRev Neurosci2019
unclearReview

Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends

Hong NBiomed Eng Lett2019
unclearReview

Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model.

Meynaghizadeh-ZargarLasers Med Sci2019810nm
positiveMouse
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