PBM Research243 studies
Photobiomodulation for Brain
243 peer-reviewed studies on light therapy for brain, spanning 1990 to 2020. Filtered from the full PBM database of 4,914 studies.
243
Total Studies
61
Human Studies
181
Positive Results
4
Wavelength Bands
Study Types
Mouse
63 (26%)
Human
61 (25%)
Rat
42 (17%)
Review
40 (16%)
Animal
18 (7%)
In vitro
13 (5%)
Outcomes
positive
181 (74%)
unclear
57 (23%)
negative
5 (2%)
Wavelength Distribution
Not specified
114 studies
Near-IR (700-900nm)
58 studies
Red (600-700nm)
54 studies
IR (900nm+)
17 studies
All Studies (243)
Photobiomodulation for Alzheimer's Disease: Translating Basic Research to Clinical Application.
EnenglJ Alzheimers Dis2020
unclearReview
Nutritional Ketosis and photobiomodulation remediate mitochondria warding off Alzheimer's disease in a diabetic, ApoE4+ patient with mild cognitive impairment: A case report.
HornerPhotodiagnosis Photodyn Ther2020810nm
positiveHuman
Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression.
KerppersLasers Med Sci2020945nm
positiveHuman
Transcranial photobiomodulation attenuates pentylenetetrazole-induced status epilepticus in peripubertal rats.
TsaiJ Biophotonics2020808nm
positiveRat
Photostimulation of cerebral and peripheral lymphatic functions
Semyachkina‐GlushkovskayaTranslational Biophotonics20201268nm
positiveMouse
Transcranial Photobiomodulation (tPBM) With 1,064-nm Laser to Improve Cerebral Metabolism of the Human Brain In Vivo.
PruittLasers Surg Med20201064nm
positiveHuman
Effects of photobiomodulation on interleukin-10 and nitrites in individuals with relapsing-remitting multiple sclerosis - Randomized clinical trial.
SilvaPLoS One2020808nm
negativeHuman
Photobiomodulation for Parkinson's Disease in Animal Models: A Systematic Review.
Salehpour & HamblinBiomolecules2020
unclearReview
Mitochondrial Dysfunction and Parkinson's Disease-Near-Infrared Photobiomodulation as a Potential Therapeutic Strategy.
FooFront Aging Neurosci2020
unclearReview
Photobiomodulation enhances mitochondrial respiration in an in vitro rotenone model of Parkinson’s disease
BikmulinaOpt Eng2020
positiveIn vitro
Light Modulation of Brain and Development of Relevant Equipment.
LiJ Alzheimers Dis2020
unclearReview
New strategies for ischemic stroke: internal photobiomodulation therapy.
Iglesias-Rey & CastilloNeural Regen Res2020
unclearAnimal
Treatment of Neurodegeneration: Integrating Photobiomodulation and Neurofeedback in Alzheimer's Dementia and Parkinson's: A Review.
Berman & NicholsPhotobiomodul Photomed Laser Surg2019
positiveHuman
New insight into Alzheimer's disease: Light reverses Aβ-obstructed interstitial fluid flow and ameliorates memory decline in APP/PS1 mice.
YueAlzheimers Dement (N Y)2019
positiveMouse
Activation of PKA/SIRT1 signaling pathway by photobiomodulation therapy reduces Aβ levels in Alzheimer's disease models.
ZhangAging Cell2019633nm
positiveMouse
Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer’s disease
ZinchenkoBiomed Opt Express20191267nm
positiveMouse
Photobiomodulation for Alzheimer’s Disease: Has the Light Dawned?
Hamblin MRPhotonics2019
unclearReview
Rapid Reversal of Cognitive Decline, Olfactory Dysfunction, and Quality of Life Using Multi-Modality Photobiomodulation Therapy: Case Report.
SalehpourPhotobiomodul Photomed Laser Surg2019
positiveHuman
Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial.
Chao LLPhotobiomodul Photomed Laser Surg2019810nm
positiveHuman
Transcranial Photobiomodulation with Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study.
MaielloPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman
Intracerebral Transcatheter Laser Photobiomodulation Therapy in the Treatment of Binswanger's Disease and Vascular Parkinsonism: Research and Clinical Experience.
Maksimovich IVPhotobiomodul Photomed Laser Surg2019633nm
positiveHuman
Transcranial Photobiomodulation to Augment Lithium in Bipolar-I Disorder.
MannuPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman
Photobiomodulation Therapy for Repeated Closed Head Injury in Rats.
YangJ Biophotonics2019808nm
positiveRat
Transcranial Photobiomodulation Therapy in the Cognitive Rehabilitation of Patients with Cranioencephalic Trauma.
CarneiroPhotobiomodul Photomed Laser Surg2019630nm
positiveHuman
Photobiomodulation preconditioning prevents cognitive impairment in a neonatal rat model of hypoxia-ischemia.
YangJ Biophotonics2019808nm
positiveRat
Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System
LeeTrans Electr Electron Mater2019810nm
positiveMouse
Brain Photobiomodulation-Preliminary Results from Regional Cerebral Oximetry and Thermal Imaging.
Litscher GMedicines (Basel)2019810nm
positiveHuman
Can Mild Cognitive Impairment Be Stabilized By Showering Brain Mitochondria With Laser Photons?
de la TorreNeuropharmacology2019
unclearReview
Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis.
SalehpourPhotobiomodul Photomed Laser Surg2019
unclearReview
Cognitive Enhancement by Transcranial Photobiomodulation Is Associated With Cerebrovascular Oxygenation of the Prefrontal Cortex.
HolmesFront Neurosci20191064nm
positiveHuman
Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives
Askalsky & IosifescuNeuropsychiatr Dis Treat2019
unclearReview
Near-infrared photobiomodulation combined with coenzyme Q10 for depression in a mouse model of restraint stress: reduction in oxidative stress, neuroinflammation, and apoptosis.
SalehpourBrain Res Bull2019810nm
positiveMouse
Transcranial photobiomodulation prevents anxiety and depression via changing serotonin and nitric oxide levels in brain of depression model mice: A study of three different doses of 810 nm laser.
EshaghiLasers Surg Med2019810nm
positiveMouse
Transcranial Photobiomodulation for Down Syndrome.
MannuPhotobiomodul Photomed Laser Surg2019830nm
positiveHuman
Brain Photobiomodulation: A New Strategy to Enhance Cognitive Function?
Gaggioli ACyberpsychol Behav Soc Netw2019
unclearAnimal
Transcranial photobiomodulation with 1064-nm laser modulates brain electroencephalogram rhythms.
WangNeurophotonics2019
positiveHuman
Transcranial near-infrared photobiomodulation could modulate brain electrophysiological features and attentional performance in healthy young adults.
JahanLasers Med Sci2019850nm
positiveHuman
Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study.
ZomorrodiSci Rep2019810nm
positiveHuman
Transcranial near-infrared stimulation may increase cortical excitability recorded in humans.
SongBrain Res Bull2019820nm
positiveHuman
Exploring the Effects of Near Infrared Light on Resting and Evoked Brain Activity in Humans Using Magnetic Resonance Imaging.
El KhouryNeuroscience2019810nm
positiveHuman
Short-term Effects of Transcranial Near-Infrared Photobiomodulation on Motor Performance in Healthy Human Subjects: An Experimental SingleBlind Randomized Clinical Trial.
FekriJ Lasers Med Sci2019808nm
positiveHuman
"Buckets": Early Observations on the Use of Red and Infrared Light Helmets in Parkinson's Disease Patients.
HamiltonPhotobiomodul Photomed Laser Surg2019
positiveHuman
Photobiomodulation Mitigates Cerebrovascular Leakage Induced by the Parkinsonian Neurotoxin MPTP.
San MiguelBiomolecules2019670nm
positiveMouse
Effect of Photobiomodulation in Rescuing Lipopolysaccharide-Induced Dopaminergic Cell Loss in the Male Sprague-Dawley Rat.
O'Brien & AustinBiomolecules2019
positiveRat
Parkinson's Disease and Light: The Bright and the Dark Sides.
MaggioBrain Res Bull2019
unclearReview
Photobiomodulation in Parkinson's disease: A randomized controlled trial
SantosBrain Stimul2019670nm
positiveHuman
Pre-conditioning with remote photobiomodulation modulates the brain transcriptome and protects against MPTP insult in mice.
GaneshanNeuroscience2019670nm
positiveMouse
Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review.
SalehpourRev Neurosci2019
unclearReview
Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends
Hong NBiomed Eng Lett2019
unclearReview
Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model.
Meynaghizadeh-ZargarLasers Med Sci2019810nm
positiveMouse